False Positives


Can a genomic test with 99.99% accuracy still produce false positives?

Yes. While it is case reportable, false positives do happen in direct to consumer genomic services. The below case highlights pitfalls in a case of long QTc syndrome.

Predham, Sarah, et al. “Case Report: Direct Access Genetic Testing and A False-Positive Result For Long QT Syndrome.” Journal of genetic counseling(2015): 1-7. http://clicks.aweber.com/y/ct/?l=C1d9c&m=lm.iS7Vz25CM6R&b=0TuJkzn43x5Cw6aTnQ0yQg

Hattip – Aime Agather, Cardiac Genetic Counselor at MedStar Washington Hospital Center