Should genetic investigations into sudden unexplained deaths focus on genes associated with cardiomyopathies and cardiac channelopathies?[scroll for answer]
Yes. A recent study by forensic medicine researchers found that 34% of individuals who suffered a sudden unexplained death (SUD) had genetic varients with a likely functional effect. Of those genetic variants, 60% were genes associated with cardiac channelopathies and 40% were genes associated with cardiomyopathies.
Christiansen, Sofie Lindgren, Christin Løth Hertz, Laura Ferrero-Miliani, Morten Dahl, Peter Ejvin Weeke, Lucamp, Gyda Lolk Ottesen, Rune Frank-Hansen, Henning Bundgaard, and Niels Morling. “Genetic Investigation of 100 Heart Genes in Sudden Unexplained Death Victims in a Forensic Setting.” European Journal of Human Genetics (2016): n. pag. Web.