Antidepressants and Side Effects

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Does genotyping P450 enzymes predict side effects in patients with depression started on nortriptyline or escitalopram? [Scroll to bottom for answer]                             … Read More

Genotyping vs Sequencing

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What is the difference between genotyping and sequencing? Sequencing determines the exact base pairs in a certain span of DNA, such as every ATCG in the whole prothrombin gene. Genotyping is the process of determining … Read More

False Positives

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Can a genomic test with 99.99% accuracy still produce false positives? Yes. While it is case reportable, false positives do happen in direct to consumer genomic services. The below case highlights pitfalls in a case … Read More

Genotyping for clopidogrel after PCI

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Does genotyping patients for their clopidogrel metabolizer status add any value to platelet function tests after PCI? Genetic clopidogrel metabolizer status is a good marker of clopidogrel response but does not add value to the … Read More